European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update

The European Association of Urology (EAU) Guidelines Panel on Upper Urinary Tract Urothelial Carcinoma (UTUC) has prepared updated guidelines to aid clinicians in the current evidence-based management UTUC and incorporate recommendations into clinical practice. To provide an overview EAU as clinicians. provided are based a thorough review available articles identified following systematic search Medline. Data urothelial malignancies were searched using keywords: urinary tract cancer, carcinomas, upper carcinoma, renal pelvis, ureter, bladder chemotherapy, ureteroscopy, nephroureterectomy, neoplasm, adjuvant treatment, instillation, recurrence, risk factors, survival. References weighted by panel experts. Owing rarity UTUC, there insufficient data strong recommendations. 2017 tumour, node, metastasis (TNM) classification is recommended. Recommendations given for diagnosis stratification well radical conservative prognostic factors discussed. A single postoperative dose intravesical mitomycin after nephroureterectomy reduces tumour recurrence. Kidney-sparing should be offered primary treatment option patients with low-risk two functional kidneys. After cisplatin-based chemotherapy indicated locally advanced UTUC. These contain information individual according standardised approach. Urologists take account specific characteristics each patient when determining optimal regimen, proposed these tumours. carcinoma rare, but because 60% tumours invasive at diagnosis, appropriate most important. number known exist.